Hydroxymetronidazole-d4(Synonyms: Metronidazole-OH-d4)

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Hydroxymetronidazole-d4 (Synonyms: Metronidazole-OH-d4)

Hydroxymetronidazole-d4 (Metronidazole-OH-d4) 是 Hydroxymetronidazole 的氘代物。Hydroxymetronidazole (Metronidazole-OH) 是一种 Metronidazole 的代谢产物，属于硝基咪唑类。Hydroxymetronidazole 可用于研究家禽中的某些细菌和原生动物疾病，以及牛痢疾和牛生殖器滴虫病。

Hydroxymetronidazole-d4 Chemical Structure

CAS No. : 1215071-08-1

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生物活性	Hydroxymetronidazole-d4 (Metronidazole-OH-d4) is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle^[1].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	191.18
Formula	C₆H₅D₄N₃O₄
CAS 号	1215071-08-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Rodrigo H M M Granja, et al. Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(6):970-6.

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