Nicarbazin-d8

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Nicarbazin-d8 

Nicarbazin-d8 是 Nicarbazin 氘代物。Nicarbazin 是一种用于鸡的有效的抗球虫剂

Nicarbazin-d8

Nicarbazin-d8 Chemical Structure

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生物活性

Nicarbazin-d8 is deuterium labeled Nicarbazin. Nicarbazin is an effective anticoccidial agent for chickens[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

434.43

Formula

C19H10D8N6O6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ott, W. H., et al. Biological Studies on Nicarbazin, a New Anticoccidial Agent. Poultry Science. 1956. 35(6), 1355–1367.

    [3]. CUCKLER AC, et al. The effect of nicarbazin on the development of immunity to avian coccidia. J Parasitol. 1956 Dec;42(6):593-607.

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