L-Lysine-15N dihydrochloride

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
L-Lysine-15N dihydrochloride 

L-Lysine-15N (dihydrochloride) 是一种 15N 标记的 Deruxtecan。Deruxtecan 是毒性药物和 linker 的偶联物。毒性药物是 DX-8951 (DXd) 衍生物，linker 是马来酰亚胺-GGFG 肽。Deruxtecan 可用于合成 DS-8201 和 U3-1402。

L-Lysine-15N dihydrochloride

L-Lysine-15N dihydrochloride Chemical Structure

CAS No. : 204451-50-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-Lysine-15N (dihydrochloride) is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

220.10

Formula

C6H16Cl2N15NO2
CAS 号

204451-50-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-239.

    [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-239.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务