2-Nitrobenzaldehyde semicarbazone-13C,15N2-1

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2-Nitrobenzaldehyde semicarbazone-13C,15N2-1 

2-Nitrobenzaldehyde semicarbazone-13C,15N2-1 是 13C,15N2 标记的 2-Nitrobenzaldehyde semicarbazone。2-Nitrobenzaldehyde Semicarbazone 是 Semicarbazide 的衍生物。2-Nitrobenzaldehyde Semicarbazone 可以用作代谢物标记,以检测被广泛禁止的抗生素呋喃西林 (Nitrofurazone)。

2-Nitrobenzaldehyde semicarbazone-13C,15N2-1

2-Nitrobenzaldehyde semicarbazone-13C,15N2-1 Chemical Structure

CAS No. : 957509-32-9

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生物活性

2-Nitrobenzaldehyde semicarbazone-13C,15N2-1 is the 13C,15N2 labeled 2-Nitrobenzaldehyde semicarbazone. 2-Nitrobenzaldehyde Semicarbazone is a derivative of Semicarbazide. 2-Nitrobenzaldehyde Semicarbazone can be measured as a metabolite marker to detect the widely banned antibiotic Nitrofurazone.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

211.15

Formula

C713CH8N215N2O3

CAS 号

957509-32-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

    [2]. Abernethy GA, et, al. Generation of semicarbazide from natural azine development in foods, followed by reaction with urea compounds. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(9):1416-30.

    [3]. Zhang S, et, al. A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2015 Dec;407(30):8971-7.

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