Inosine-13C(Synonyms: 肌苷 13C；次黄苷 13C；次黄嘌呤核苷 13C；肌甙 13C)

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Inosine-13C (Synonyms: 肌苷 13C；次黄苷 13C；次黄嘌呤核苷 13C；肌甙 13C)

Inosine-13C 是 13C 标记的 Inosine。 Inosine 是一种由腺苷分解代谢产生的内源性嘌呤核苷。Inosine 具有抗炎免疫调节，抗伤害和神经保护作用。Inosine 是腺苷受体 A1R 和 A2AR 的激动剂。

Inosine-13C(Synonyms: 肌苷 13C；次黄苷 13C；次黄嘌呤核苷 13C；肌甙 13C)

Inosine-13C Chemical Structure

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生物活性

Inosine-13C is the 13C labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

269.22

Formula

C913CH12N4O5
中文名称

肌苷 13C；次黄苷 13C；次黄嘌呤核苷 13C；肌甙 13C
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Filipe Marques Gonçalves, et al. Signaling pathways underlying the antidepressant-like effect of inosine in mice. Purinergic Signal. 2017 Jun; 13(2): 203-214.;Ajith A. Welihinda, et al. The adenosine metabolite inosine is a functional agonist of the adeno

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