D-(+)-Trehalose-d14(Synonyms: D-Trehalose-d14; α,α-Trehalose-d14)

发表于由

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D-(+)-Trehalose-d14 (Synonyms: D-Trehalose-d14; α,α-Trehalose-d14)

D-(+)-Trehalose-d14 是 D-(+)-Trehalose 的氘代物。 D-(+)-Trehalose可从 Saccharomyces cerevisiae 中分离得到，常用作食品成分和药物赋形剂。

D-(+)-Trehalose-d14(Synonyms: D-Trehalose-d14; α,α-Trehalose-d14)

D-(+)-Trehalose-d14 Chemical Structure

CAS No. : 2028292-31-9

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生物活性

D-(+)-Trehalose-d14 is the deuterium labeled D-(+)-Trehalose. D-(+)-Trehalose, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipi[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

356.38

Formula

C12H8D14O11
CAS 号

2028292-31-9
中文名称

α,α-海藻糖 d14；α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷 d14；D-海藻糖,无水 d14
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (499 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

    [2]. Megarry AJ, et al. Amorphous trehalose dihydrate by cryogenic milling. Carbohydr Res. 2011 Jun 1;346(8):1061-4.

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