标签归档：寡霉素

Oligomycin C (Synonyms: 寡霉素C)

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Oligomycin C  (Synonyms: 寡霉素C)

Oligomycin C 是由链霉菌产生的大环内酯类抗生素。Oligomycin C 对Aspergillus niger，Alternaria alternata，Botrytis cinerea，Phytophthora capsici 表现出较强的抗黑曲霉活性，但对细菌没有活性。

Oligomycin C (Synonyms: 寡霉素C)

Oligomycin C Chemical Structure

CAS No. : 11052-72-5

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生物活性

Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria[1].

IC50 & Target

Macrolide

 

体外研究
(In Vitro)

Interaction of oligomycin C with purified CYP107W1 results in a type I binding with Kd value of 14.4 μM[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Oligomycin C 相关抗体:
分子量

775.06

Formula

C45H74O10
CAS 号

11052-72-5
中文名称

寡霉素C
结构分类
  • Antibiotics
  • Disease Research
  • Antifungal
  • Antibiotics
  • Macrolide Antibiotics
初始来源
  • 微生物

Streptomyces
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (535 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Yang PW, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus. Folia Microbiol (Praha). 2010;55(1):10-16.  [Content Brief]

    [2]. Han S, et al. Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch Biochem Biophys. 2015;575:1-7.  [Content Brief]

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