标签归档：查尔酮

4′-Hydroxy-2,4-dimethoxychalcone (Synonyms: 4-O-甲基刺甘草查尔酮)

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4′-Hydroxy-2,4-dimethoxychalcone  (Synonyms: 4-O-甲基刺甘草查尔酮) 纯度: 99.76%

4′-Hydroxy-2,4-dimethoxychalcone 是龙血天竺葵红色草药树脂中的天然查尔酮衍生物。4′-Hydroxy-2,4-dimethoxychalcone 具有广泛的生物学活性，包括抗疟疾，抗原生动物，抗细菌，抗真菌活性。

4

4′-Hydroxy-2,4-dimethoxychalcone Chemical Structure

CAS No. : 151135-64-7

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5 mg ￥2200 In-stock
10 mg ￥3800 In-stock
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4′-Hydroxy-2,4-dimethoxychalcone 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library
  • Natural Product Library
  • Antifungal Compound Library
  • Antibacterial Compound Library
  • Phenols Library
  • Flavonoids Library
  • Antiparasitic Compound library
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  • Multi-Target Compound Library

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生物活性

4′-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4′-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2].

体外研究
(In Vitro)

4′-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 μM) and W2 (IC50=4.8 μM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

4′-Hydroxy-2,4-dimethoxychalcone 相关抗体:
体内研究
(In Vivo)

4′-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

284.31

Formula

C17H16O4
CAS 号

151135-64-7
性状

固体

颜色

Light yellow to yellow

中文名称

4-O-甲基刺甘草查尔酮
结构分类
  • Flavonoids
  • Chalcones
  • Phenols
  • Monophenols
初始来源
  • 植物
  • 菊科
  • 伞序托鞭菊
  • 植物
  • 伞形科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 99.76%

Data Sheet (527 KB) SDS (251 KB)

COA (167 KB) HNMR (124 KB) RP-HPLC (137 KB) MS (211 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Clare E Gutteridge, et al. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Pharmacology. 2011;87(1-2):96-104.  [Content Brief]

    [2]. Qing-An Zheng, et al. Flavonoids from the Resin of Dracaena cochinchinensis. Helvetica Chimica Acta, 87(5), 1167–1171.

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