标签归档：毒肽

Phallacidin (Synonyms: 羧基二羟鬼笔毒肽)

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Phallacidin  (Synonyms: 羧基二羟鬼笔毒肽) 纯度: ≥92.0%

Phallacidin 是蘑菇毒素的鬼笔毒素家族的成员。Phallacidin 结合 F-肌动蛋白。

Phallacidin (Synonyms: 羧基二羟鬼笔毒肽)

Phallacidin Chemical Structure

CAS No. : 26645-35-2

规格 价格 是否有货 数量
1 mg ￥8900 In-stock
5 mg   询价  
10 mg   询价  

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Phallacidin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin[1].

分子量

846.90

Formula

C37H50N8O13S
CAS 号

26645-35-2
性状

固体

颜色

White to off-white

Sequence

Ala-Trp-Leu-Val-{D-Asp}-Cys-{Hyp} (Sulfide bridge: Trp2- Cys6)
Sequence Shortening

AWLV-{D-Asp}-C-{Hyp} (Sulfide bridge: Trp2- Cys6)
中文名称

羧基二羟鬼笔毒肽
结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 微生物

Amanita exitialis basidiocarps
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料

纯度: ≥92.0%

Data Sheet (513 KB) SDS (252 KB)

COA (178 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. L S Barak, et al. Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin. Proc Natl Acad Sci U S A. 1980 Feb;77(2):980-4.  [Content Brief]

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