标签归档：牛膝

25S-Inokosterone (Synonyms: 25S-牛膝甾酮)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
25S-Inokosterone  (Synonyms: 25S-牛膝甾酮)

25S-Inokosterone 是一种植物蜕皮激素，存在于两个相同的 A. bidentata Blume 和A. japonica Nakai，以及两个不同物种 C. capitata Moq 和 C. officinalis Kuan 的根中。25S-Inokosterone 具有用于 LPS 诱发的急性肾损伤研究的潜力。

25S-Inokosterone (Synonyms: 25S-牛膝甾酮)

25S-Inokosterone Chemical Structure

CAS No. : 19595-18-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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25S-Inokosterone 相关产品

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生物活性

25S-Inokosterone is a phytoecdysone in the roots of two same species of A. bidentata Blume and A. japonica Nakai, and two different species of C. capitata Moq and C. officinalis Kuan. 25S-Inokosterone has the potential for the LPS-induced acute kidney injury research[1][2].

体外研究
(In Vitro)

25S-Inokosterone (10 μM) significantly promotes the proliferation of LPS-induced NRK52e cells (1.0 μg/mL LPS). 25S-Inokosterone significantly reduces the rate of NRK52e cells apoptosis[1].
25S-Inokosterone shows weak inhibitory activity for thymus and activation-regulated chemokine expression levels in TNF-α plus IFN-γ induced HaCaT cells. 25S-Inokosterone exhibits the most potent inhibition (80-95% at 200 µg/mL) against TNF-α expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

25S-Inokosterone 相关抗体:
分子量

480.63

Formula

C27H44O7
CAS 号

19595-18-7
中文名称

25S-牛膝甾酮
结构分类
  • Others
初始来源
  • 植物
  • 苋科
  • 头花杯苋
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Shengchao Wang, et al. Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway. Biomed Pharmacother  [Content Brief]

    [2]. Bing Tian Zhao, et al. High performance liquid chromatography used for quality control of Achyranthis Radix. Arch Pharm Res. 2012 Aug;35(8):1449-55.  [Content Brief]

    [3]. K. Kim, et al.Phytoecdysones from the Roots of Achyranthes japonica Nakai and their Anti-atopy Activity. J Appl Biol Chem (2015) 58(1), 13-19.

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