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Medicarpin (Synonyms: 美迪紫檀素) 纯度: 99.70%
Medicarpin 是一种从紫花苜蓿中分离出的类黄酮。Medicarpin 通过调节 P-gp 介导的活性分子外流，诱导白血病 P388 细胞凋亡 (apoptosis) 并克服多药耐药性。
Medicarpin Chemical Structure
CAS No. : 32383-76-9
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥1100 | In-stock | |
| 5 mg | ￥2800 | In-stock | |
| 10 mg | ￥4340 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
* Please select Quantity before adding items.
Medicarpin 相关产品
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| 生物活性 |
Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of agents[1]. |
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| 体外研究 (In Vitro) |
Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
270.28 |
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| Formula |
C16H14O4 |
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| CAS 号 |
32383-76-9 |
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| 性状 |
固体 |
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| 颜色 |
Off-white to light yellow |
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| 中文名称 |
美迪紫檀素 |
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| 结构分类 |
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| 初始来源 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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| 溶解性数据 |
In Vitro:
DMSO 中的溶解度 : 50 mg/mL (184.99 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO) 配制储备液
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
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给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗，建议您多配一只动物的量
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工作液所需浓度 : mg/mL
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| 纯度 & 产品资料 |
纯度: 99.70%
Data Sheet (599 KB) SDS (393 KB)
COA (172 KB) HNMR (258 KB) LCMS (88 KB) 产品使用指南 (1538 KB) |
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| 参考文献 |
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