标签归档：镰孢

Enniatin A (Synonyms: 镰孢菌素 A)

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Enniatin A  (Synonyms: 镰孢菌素 A)

Enniatin A 是一种镰刀菌毒素。在大鼠肝微粒体酶实验中，Enniatin A 抑制酰基辅酶 A：胆固醇酰基转移酶 (ACAT) 活性，IC50 为 22 μM。

Enniatin A (Synonyms: 镰孢菌素 A)

Enniatin A Chemical Structure

CAS No. : 2503-13-1

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生物活性

Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes[1].

IC50 & Target[1]

ACAT

 

体外研究
(In Vitro)

Enniatin A exhibits cytotoxic effects in HeLa cell lines with IC50s of 1.15 μM concentration for 24 h and 0.57 μM concentration for 48 h[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Enniatin A 相关抗体:
分子量

681.90

Formula

C36H63N3O9
CAS 号

2503-13-1
中文名称

镰孢菌素 A；恩镰孢菌素 A
结构分类
  • Antibiotics
  • Disease Research
  • Antibacterial
  • Antibiotics
  • Macrolide Antibiotics
初始来源
  • 微生物

Fusarium sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (534 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32.  [Content Brief]

    [2]. Mamur S, et al. Assessment of cytotoxic and genotoxic effects of enniatin-A in vitro. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Aug;35(8):1633-1644.  [Content Brief]

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