标签归档：argininosuccinic

Argininosuccinic acid disodium

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Argininosuccinic acid disodium  纯度: ≥96.0%

Argininosuccinic acid disodium 参与尿素循环的第四步，被精氨酸琥珀酸裂解酶 (ASL) 裂解为精氨酸和富马酸。Argininosuccinic acid disodium 降低还原型谷胱甘肽 (GSH) 浓度，增加大脑皮层和纹状体的活性氧生成。Argininosuccinic acid disodium 可引起脂质过氧化和蛋白质氧化，还在发育中大鼠脑中诱导氧化应激。

Argininosuccinic acid disodium

Argininosuccinic acid disodium Chemical Structure

CAS No. : 918149-29-8

规格 价格 是否有货 数量
5 mg ￥2300 In-stock
10 mg ￥3700 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Argininosuccinic acid disodium 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Metabolism/Protease Compound Library
  • NF-κB Signaling Compound Library
  • Stem Cell Signaling Compound Library
  • Natural Product Library
  • Anti-Aging Compound Library
  • Antioxidant Compound Library
  • Oxygen Sensing Compound Library
  • Ferroptosis Compound Library
  • Pyroptosis Compound Library
  • Anti-Parkinson’s Disease Compound Library
  • Neurodegenerative Disease-related Compound Library
  • Mitochondria-Targeted Compound Library
  • Anti-Pulmonary Fibrosis Compound Library
  • Cuproptosis Compound Library
  • Metabolic Enzyme Compound Library
  • Radioprotector Library

•同靶点产品:

•同靶点蛋白产品:

生物活性

Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].

分子量

334.24

Formula

C10H16N4Na2O6
CAS 号

918149-29-8
性状

固体

颜色

White to off-white

结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥96.0%

Data Sheet (528 KB) SDS (251 KB)

COA (190 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244.  [Content Brief]

    [2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务