标签归档：carnitine

D-Carnitine hydrochloride (Synonyms: D-左旋肉碱盐酸盐; (S)-Carnitine hydrochloride)

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D-Carnitine hydrochloride  (Synonyms: D-左旋肉碱盐酸盐; (S)-Carnitine hydrochloride)

D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) 已被用于研究麦角硫因素转运蛋白 SLC22A4 和肉毒碱转运蛋白 SLC22A5。D-Carnitine hydrochloride还被用于使棕榈酸进入线粒体。

D-Carnitine hydrochloride (Synonyms: D-左旋肉碱盐酸盐; (S)-Carnitine hydrochloride)

D-Carnitine hydrochloride Chemical Structure

CAS No. : 10017-44-4

规格 价格 是否有货 数量
5 mg ￥326 1 周
10 mg   询价  
50 mg   询价  

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D-Carnitine hydrochloride 相关产品

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生物活性

D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) has been used to study sulfur factor transporter SLC22A4 and carnitine transporter SLC22A5 in ergot. D-Carnitine hydrochloride is also used to get palmitic acid into mitochondria[1][2].

IC50 & Target[1]

Human Endogenous Metabolite

 

体外研究
(In Vitro)

When expressed in human embryonic kidney (HEK)293 cells, hOCTN2 (SLC22A5) shows low but significant stereospecific transport activity: D-carnitine is transported with lower affinity (Km=10.9 μM) than the L-isomer (Km=4.3 μM)[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

D-Carnitine hydrochloride 相关抗体:
分子量

197.66

Formula

C7H16ClNO3
CAS 号

10017-44-4
中文名称

D-左旋肉碱盐酸盐
结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro: 

H2O 中的溶解度 : 125 mg/mL (632.40 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.0592 mL 25.2960 mL 50.5919 mL
5 mM 1.0118 mL 5.0592 mL 10.1184 mL
10 mM 0.5059 mL 2.5296 mL 5.0592 mL

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纯度 & 产品资料
Data Sheet (597 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Horvath GA, et al. Newborn screening for MCAD deficiency: experience of the first three years in British Columbia, Canada. Can J Public Health. 2008 Jul-Aug;99(4):276-80.  [Content Brief]

    [2]. Leenders JJ, et al. Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity. J Biol Chem. 2010 Aug 27;285(35):27449-56.  [Content Brief]

    [3]. Ohashi R, et al. Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J Pharmacol Exp Ther. 1999 Nov;291(2):778-84.  [Content Brief]

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