(±)-Catechin (Synonyms: (+/-)-儿茶精; rel-Cianidanol; rel-Catechuic acid)

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(±)-Catechin  (Synonyms: (+/-)-儿茶精; rel-Cianidanol; rel-Catechuic acid) 纯度: 98.38%

(±)-Catechin (rel-Cianidanol) 是绿茶多酚 Catechin 的外消旋体。Catechin 具有抗癌活性,并诱导细胞凋亡。(±)-Catechin 具有两种形式 (+)-Catechin 及其对映体 (-)-Catechin。(+)-Catechin 抑制环氧合酶-1 (COX-1) 的 IC50 为 1.4 μM。(-)-Catechin 则能够有效促进 hBM-MSC 脂肪细胞分化,增加脂联素、PPARγ 水平。(±)-Catechin 具有抗肿瘤,抗肥胖,抗糖尿病,抗心血管,抗感染,保肝和神经保护作用。

(±)-Catechin                                          (Synonyms: (+/-)-儿茶精; rel-Cianidanol;  rel-Catechuic acid)

(±)-Catechin Chemical Structure

CAS No. : 7295-85-4

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(±)-Catechin 相关产品

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生物活性

(±)-Catechin (rel-Cianidanol) This is a green tea polyester. Catechin possesses anti-cancer activity, which has led to its demise. (±)-Catechin 具有两种forms (+)-Catechin and its reflection body (-)-Catechin. (+)-Catechin inhibitory environment-1 (COX-1) IC50 为 1.4 μM. (-)-Catechin has the effect of promoting hBM-MSC adipose cell differentiation, increasing adipose tissue, and PPARγ horizontal. (±)-Catechin has anti-diabetic, anti-hypertrophic, anti-diabetic, anti-cardiovascular, anti-infective, and liver-protecting effects.

体外研究
(In Vitro)

(-)-Catechin (10 μM; 2 天一周期,共 12 天) 诱导人骨髓间充质干细胞(hBM-MSC)脂肪细胞分化,增加脂联素水平、增加 PPARγ 转录[2]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

(±)-Catechin 相关抗体:

分子量

290.27

Formula

C15H14O6

CAS 号

7295-85-4

性状

固体

颜色

White to off-white

中文名称

(±)-儿茶素

结构分类
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 山茶科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 125 mg/mL (430.63 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.4451 mL 17.2253 mL 34.4507 mL
5 mM 0.6890 mL 3.4451 mL 6.8901 mL
10 mM 0.3445 mL 1.7225 mL 3.4451 mL

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* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

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浓度

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体积

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分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

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体积 (start)

V1

=

浓度 (final)

C2

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体积 (final)

V2

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给药剂量

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计算结果
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纯度 & 产品资料

纯度: 98.38%

Data Sheet (606 KB) SDS (393 KB)

COA (271 KB) HNMR (286 KB) LCMS (250 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Mamoru Isemura. Catechin in Human Health and Disease. Molecules. 2019 Feb 1;24(3):528.  [Content Brief]

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