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Cholic acid sodium (Synonyms: 胆酸钠; Sodium cholate) 纯度: 99.41%
Cholic acid sodium 是肝脏中产生的主要胆汁酸，通常与甘氨酸或牛磺酸缀合，有助于脂肪吸收和胆固醇排泄。Cholic acid sodium 具有口服活性。
Cholic acid sodium Chemical Structure
CAS No. : 361-09-1
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 10 mM * 1 mL in Water | ￥660 | In-stock | |
| 100 mg | ￥600 | In-stock | |
| 200 mg | 询价 | ||
| 500 mg | 询价 |
* Please select Quantity before adding items.
Cholic acid sodium 相关产品
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| 生物活性 |
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2]. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
Cholic acid sodium (1 mg/mL，30 分钟) 竞争性结合 HepG2 细胞上的 Na+/牛磺胆酸盐协同转运多肽 (NTCP)，并显著抑制 Cholic acid sodium (CA)-纳米脂质体 (LP)-多柔比星的摄取 (DOX)-HCl，这表明 CA-LPs-DOX-HCl 也通过 NTCP 介导的内吞途径被摄取[1]。 Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
Cholic acid sodium (1% (w/w) 胆酸补充饮食；口服；14 天) 可能通过上调 miR142-3p 降低 SHP (小异二聚体伴侣) 蛋白表达。胆酸增加 CYP2D6 的表达和活性[2]。 Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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| Clinical Trial |
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| 分子量 |
430.55 |
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| Formula |
C24H39NaO5 |
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| CAS 号 |
361-09-1 |
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| 性状 |
固体 |
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| 颜色 |
White to off-white |
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| 中文名称 |
胆酸钠 |
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| 结构分类 |
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| 初始来源 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| 溶解性数据 |
In Vitro:
H2O 中的溶解度 : ≥ 250 mg/mL (580.65 mM) * “≥” means soluble, but saturation unknown. 配制储备液
查看完整储备液配制表
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 * 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
In Vivo:
以下溶解方案，请直接配置工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。
动物溶解方案计算器
请输入动物实验的基本信息：
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
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| 纯度 & 产品资料 |
纯度: 99.41%
Data Sheet (618 KB) SDS (0 KB)
COA (197 KB) RP-HPLC (178 KB) 产品使用指南 (1538 KB) |
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| 参考文献 |
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