标签归档：demethyl

Higenamine (Synonyms: 去甲乌药碱; Norcoclaurine; Demethyl-Coclaurine)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Higenamine  (Synonyms: 去甲乌药碱; Norcoclaurine; Demethyl-Coclaurine)

Higenamine (Norcoclaurine) 是一种 β2-AR 激动剂，是中药乌头的关键成分，可用于心力衰竭的的研究。Higenamine (Norcoclaurine) 具有抗凋亡作用。

Higenamine (Synonyms: 去甲乌药碱; Norcoclaurine; Demethyl-Coclaurine)

Higenamine Chemical Structure

CAS No. : 5843-65-2

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Higenamine 的其他形式现货产品:

Higenamine hydrochloride (S)-Higenamine hydrobromide

Higenamine 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Higenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine (Norcoclaurine) has anti-apoptotic effects[1][2].

IC50 & Target

β adrenergic receptor

 

Clinical Trial

分子量

271.31

Formula

C16H17NO3
CAS 号

5843-65-2
中文名称

去甲乌药碱
结构分类
  • Alkaloids
  • Isoquinoline Alkaloids
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 毛茛科
  • 乌头
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Wu MP, et al. Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway. Pharmacol Res. 2016 Feb;104:115-23.  [Content Brief]

    [2]. Lee SR, et al. Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acidsand energy expenditure in human subjects. Lipids Health Dis. 2013 Oct 21;12:148.  [Content Brief]

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