Cap-dependent endonuclease-IN-4

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Cap-dependent endonuclease-IN-4 

Cap-dependent endonuclease-IN-4 是一种有效的 cap-dependent 核酸内切酶 (CEN) 抑制剂。Cap-dependent endonuclease-IN-4 是一种多环氨基甲酰基吡啶酮衍生物。Cap-dependent endonuclease-IN-4 选择性地阻断流感病毒的转录过程,从而抑制流感病毒的增殖。Cap-dependent endonuclease-IN-4 具有研究流感病毒引起的感冒的潜力 (信息摘自专利 WO2019196891A1,化合物 1B)。

Cap-dependent endonuclease-IN-4

Cap-dependent endonuclease-IN-4 Chemical Structure

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生物活性

Cap-dependent endonuclease-IN-4 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-4 is a polycyclic carbamoylpyridone derivative. Cap-dependent endonuclease-IN-4 selectively blocks the transcriptional process of influenza virus, thus inhibits influenza virus multiplication. Cap-dependent endonuclease-IN-4 has the potential for the research of colds caused by influenza viruses (extracted from patent WO2019196891A1, compound 1B)[1].

分子量

572.56

Formula

C27H22DF2N3O7S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xiaoyun Zhu, et al. Polycyclic carbamoylpyridone derivatives, pharmaceutical compositions and uses thereof. Patent WO2019196891A1.

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