标签归档：glu

Epsilon-(gamma-glutamyl)-lysine (Synonyms: H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Epsilon-(gamma-glutamyl)-lysine  (Synonyms: H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys)

Epsilon-(gamma-glutamyl)-lysine 是 N(6)-acyl-L-lysine 的衍生物。在一些疾病中 (如非糖尿病肾病，青光眼)，组织转谷氨酰胺酶 (tTg) 使得 ECM 成分之间形成 Epsilon-(gamma-glutamyl)-lysine 键增加。

Epsilon-(gamma-glutamyl)-lysine (Synonyms: H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys)

Epsilon-(gamma-glutamyl)-lysine Chemical Structure

CAS No. : 17105-15-6

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Epsilon-(gamma-glutamyl)-lysine 的其他形式现货产品:

Epsilon-(gamma-glutamyl)-lysine TFA

Epsilon-(gamma-glutamyl)-lysine 相关产品

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生物活性

Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].
IC50 & Target

Human Endogenous Metabolite

 

分子量

275.30

Formula

C11H21N3O5
CAS 号

17105-15-6
结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (524 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45.  [Content Brief]

    [2]. A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.  [Content Brief]

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