标签归档：guanylic

4-Methoxyestrone-13C6

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4-Methoxyestrone-13C6 

4-Methoxyestrone-13C6 是一种 13C 标记的 5′-Guanylic acid。5′-Guanylic acid (5′-GMP) 与几种代谢紊乱有关，包括 aica-核糖体途径、腺苷脱氨酶缺乏症、腺嘌呤磷酸转移酶缺乏症 (aprt) 以及 2-羟基葡糖酸盐途径。

4-Methoxyestrone-13C6

4-Methoxyestrone-13C6 Chemical Structure

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生物活性

4-Methoxyestrone-13C6 is a 13C-labeled 5′-Guanylic acid. 5′-Guanylic acid (5′-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

306.35

Formula

C1313C6H24O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-235.

    [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-235.

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