标签归档：heparin

Heparin (Synonyms: 肝素)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Heparin  (Synonyms: 肝素)

Heparin 是硫酸粘多糖，是注射抗凝剂，是负电荷密度最高的生物分子。Heparin 显著抑制外泌体-细胞相互作用。

Heparin (Synonyms: 肝素)

Heparin Chemical Structure

CAS No. : 9005-49-6

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Heparin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Heparin (6 天) 可降低 HIV 对 MT-4 细胞的细胞致病性，IC50 为 7.5 μg/mL[2]。
Heparin (0.5 U/mL，48 小时) 抑制 SGHPL-4 细胞系中 HGF 诱导的滋养层侵袭[3]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Heparin 相关抗体:
Clinical Trial

CAS 号

9005-49-6
中文名称

肝素；肝磷脂
结构分类
  • Saccharides
  • Polysaccharides
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (543 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):391-412.  [Content Brief]

    [2]. Ito M, et al. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro. Antiviral Res. 1987 Jul;7(6):361-7.  [Content Brief]

    [3]. Ganapathy R, et al. Effect of heparin and fractionated heparin on trophoblast invasion. Hum Reprod. 2007 Sep;22(9):2523-7.  [Content Brief]

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