Hydroxypyruvic acid lithium hydrate (Synonyms: β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Hydroxypyruvic acid lithium hydrate  (Synonyms: β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate)

Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) 是甘氨酸、丝氨酸和苏氨酸代谢的中间产物 (intermediate)。Hydroxypyruvic acid lithium hydrate 是丝氨酸-丙酮酸氨基转移酶和乙醛酸还原酶/羟基丙酮酸还原酶的底物 (substrate)。Hydroxypyruvic acid lithium hydrate 参与了二甲基甘氨酸脱氢酶缺乏症的代谢紊乱途径。

Hydroxypyruvic acid lithium hydrate                                          (Synonyms: β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate)

Hydroxypyruvic acid lithium hydrate Chemical Structure

CAS No. : 209728-15-4

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Hydroxypyruvic acid lithium hydrate 的其他形式现货产品:

Hydroxypyruvic acid

Hydroxypyruvic acid lithium hydrate 相关产品

同靶点产品:

同靶点蛋白产品:

生物活性

Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

IC50 & Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

Hydroxypyruvic acid (lithium hydrate) (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

128.01

Formula

C3H5LiO5

CAS 号

209728-15-4

结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
  • 人肠道微生物代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Teerajetgul Y, et al. Oxalate synthesis from hydroxypyruvate in vitamin-B6-deficient rats.Urol Res. 2007 Aug;35(4):173-8. Epub 2007 Jun 13.  [Content Brief]

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务