Isochondrodendrine (Synonyms: Isochondrodendrin)

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Isochondrodendrine  (Synonyms: Isochondrodendrin)

Isochondrodendrine ( Isochondrodendrin) 是一类从 Isolona ghesquiereina 中分离出来的双苄基异喹啉生物碱。Isochondrodendrine 对 Plasmodium falciparum 具有很强的抗疟原虫活性。

Isochondrodendrine                                          (Synonyms: Isochondrodendrin)

Isochondrodendrine Chemical Structure

CAS No. : 477-62-3

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Isochondrodendrine 相关产品

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生物活性

Isochondrodendrine ( Isochondrodendrin) is a class of bisbenzylisoquinoline alkaloid isolated from Isolona ghesquiereina. Isochondodendrine has strong antiplasmodial activity against Plasmodium falciparum[1].

IC50 & Target

Plasmodium falciparum[1]

体内研究
(In Vivo)

Isochondrodendrine has strong in vitro antiplasmodial activity against the chloroquine resistant strain FMC29 of Plasmodium falciparum. Toxicity observed is 50 to 100 fold greater towards Plasmodium falciparum than cultured L6 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

594.70

Formula

C36H38N2O6

CAS 号

477-62-3

结构分类
  • Alkaloids
  • Isoquinoline Alkaloids
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 凤尾蕨科
  • 半月形铁线蕨
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (541 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Mambu L, et al. Spectral characterisation and antiplasmodial activity of bisbenzylisoquinolines from Isolona ghesquiereina. Planta Med. 2000 Aug;66(6):537-40.  [Content Brief]

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