Isosaponarin (Synonyms: 异肥皂草苷)

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Isosaponarin  (Synonyms: 异肥皂草苷)

Isosaponarin 是一种从芥末叶中分离出的黄酮苷,可以增加胶原蛋白 (collagen) 的合成,这是由上调的 TGF-βII 型受体 (TβR-II) 和脯氨酰 4-羟化酶 (P4H) 蛋白产生引起的。

Isosaponarin                                          (Synonyms: 异肥皂草苷)

Isosaponarin Chemical Structure

CAS No. : 19416-87-6

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生物活性

Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin increases collagen synthesis, caused by up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production[1].

IC50 & Target

Collagen synthesis[1]

分子量

594.52

Formula

C27H30O15

CAS 号

19416-87-6

性状

固体

颜色

White to yellow

中文名称

异肥皂草苷

结构分类
  • Flavonoids
  • Flavones
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 石竹科
  • 王不留行
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 99.59%

Data Sheet (524 KB) SDS (251 KB)

COA (275 KB) CNMR (99 KB) RP-HPLC (259 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Masashi Nagai, et al. The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism. J Nat Med. 2010 Jul;64(3):305-12.  [Content Brief]

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