标签归档：methoxyphaseollidin

1-Methoxyphaseollidin

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
1-Methoxyphaseollidin 

1-Methoxyphaseollidin，一种类黄酮化合物，是 lysoPAF 乙酰转移酶的抑制剂，IC50 值为 48 μM。1-Methoxyphaseollidin 表现出抗幽门螺杆菌活性。

1-Methoxyphaseollidin

1-Methoxyphaseollidin Chemical Structure

CAS No. : 65428-13-9

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生物活性

1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

分子量

354.40

Formula

C21H22O5
CAS 号

65428-13-9
结构分类
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 豆科
  • 甘草
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63.  [Content Brief]

    [2]. Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6.  [Content Brief]

    [3]. Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597.  [Content Brief]

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