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Moniliformin sodium salt (Synonyms: 串珠镰刀菌素钠盐) 纯度: 99.50%
Moniliformin sodium salt是提取自镰孢镰刀菌中的有效的霉菌毒素。
Moniliformin sodium salt Chemical Structure
CAS No. : 71376-34-6
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 10 mM * 1 mL in DMSO | ￥2245 | In-stock | |
| 1 mg | ￥1700 | In-stock | |
| 5 mg | ￥3600 | In-stock | |
| 10 mg | ￥5700 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
* Please select Quantity before adding items.
Moniliformin sodium salt 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
| 生物活性 |
Moniliformin sodium salt is a potent mycotoxin isolate from Fusarium moniliforme. |
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| 体外研究 (In Vitro) |
Fusarium moniliforme NRRL 6322 produces about 600 mg of recoverable moniliformin, a mycotoxic metabolite, per kg of corn grit medium. Several strains of Fusarium moniliforme produce in laboratory culture more than 800 mg of moniliformin per kg of growth substrate[1]. Monocytes-derived macrophages exposed to moniliformin during the differentiation process present a decrease of endocytosis ability, and a decrease of CD71 and HLA-DR expression[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
Moniliformin is less toxic to mice, with an LD50 of 20.9 mg per kg for the females and 29.1 mg per kg of body weight for the males. As in the case of the chicks, mice surviving the toxin demonstrated no ill effects; the mice or chicks that died became recumbent in 4 to 6 h after treatment and died within 24 h. In 4-day-old chicken embryos, a sharp LD50 of 2.8 μg per embryo is obtained with no overt gross teratogenic effects in the survivors[1]. Rats treated with the highest dose of moniliformin show decreased activity followed by acute heart failure and death. The rats of the lower doses (<9mg>[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
120.04 |
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| Formula |
C4HNaO3 |
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| CAS 号 |
71376-34-6 |
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| 性状 |
固体 |
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| 颜色 |
Light yellow to yellow |
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| 中文名称 |
串珠镰刀菌素钠盐 |
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| 结构分类 |
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| 初始来源 |
Fusarium moniliforme |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| 溶解性数据 |
In Vitro:
H2O 中的溶解度 : 100 mg/mL (833.06 mM; 超声助溶) DMSO 中的溶解度 : ≥ 45 mg/mL (374.88 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO) * “≥” means soluble, but saturation unknown. 配制储备液
查看完整储备液配制表
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 * 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
In Vivo:
以下溶解方案，请直接配置工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。
动物溶解方案计算器
请输入动物实验的基本信息：
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
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| 纯度 & 产品资料 |
纯度: 99.50%
Data Sheet (614 KB) SDS (420 KB)
COA (171 KB) RP-HPLC (259 KB) 产品使用指南 (1538 KB) |
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| 参考文献 |
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| Animal Administration [1][3] |
Rats: Moniliformin is prepared in water. In this experiment, 5 dose groups (3, 6, 9, 12 and 15 mg/kg moniliformin b.w.) of test animals are exposed to moniliformin for 28 days. Each group consists of 5 male Sprague-Dawley rats. The dose groups are determined based on our acute toxicity study of MON in rats. In addition, a control group administered with filtered tap water and two satellite groups (dosed 12 and 15 mg/kg b.w. moniliformin) are used. The two satellite groups are kept alive for an additional 14 days without treatment to detect possible delayed toxic effects and to follow up recovery[3]. Mice: Sterile aqueous solutions of moniliformin are injected intraperitoneally (0.2 mL) into five female and five male white mice, weighing about 25 g each, at concentrations equivalent to 0, 20, 25, 30, and 35 mg per kg of body weight. The mice are observed over a 4-day period, and LD50 values are determined[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 参考文献 |
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