Neoxanthin (Synonyms: 新黄质)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Neoxanthin  (Synonyms: 新黄质) 纯度: ≥99.0%

Neoxanthin 是深绿色多叶蔬菜中的一种主要的叶黄素类胡萝卜素,是一种植物激素脱落酸的前体。Neoxanthin 是一种有效的抗氧化剂和集光颜料,诱导细胞凋亡 (apoptosis) 并具有抗癌作用。

Neoxanthin                                          (Synonyms: 新黄质)

Neoxanthin Chemical Structure

CAS No. : 14660-91-4

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生物活性

Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions[1][2].

体外研究
(In Vitro)

Neoxanthin (20 μM; 72 h) treatment significantly reduces cell viability to 10.9% for PC-3 cells, 15.0% for DU 145 cells, and nearly zero for LNCaP cells, respectively[1].
Neoxanthin strongly inhibits cell growth by suppressing DNA synthesis in C3H10T1/2 cells[1].
In photosynthetic organisms, Neoxanthin is the essential component of both the photosystem I (PSI) and photosystem II (PSII) reaction centers of oxygenic photosynthetic apparatus[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Neoxanthin 相关抗体:

体内研究
(In Vivo)

The gastrointestinal metabolism of Neoxanthin in mice is investigated. Two hours after the oral administration of Neoxanthin (40 nmol/mouse), Neoxanthin is found in the plasma and livers of mice. The concentrations of Neoxanthin is 13.6-9.0 nM in plasma, and 7.3 3.6 pmol/g in liver, respectively. (R/S)-Neochrome is also found in the small intestinal contents of Neoxanthin-administered mice[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

600.87

Formula

C40H56O4

CAS 号

14660-91-4

性状

固体

颜色

Light yellow to yellow

中文名称

新黄质

结构分类
  • Others
初始来源
  • 植物
  • 其他科
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (531 KB) SDS (251 KB)

COA (263 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. E Kotake-Nara, et al. Carotenoids Affect Proliferation of Human Prostate Cancer Cells. J Nutr. 2001 Dec;131(12):3303-6.  [Content Brief]

    [2]. Ramesh Kumar Saini, et al. An Efficient One-Step Scheme for the Purification of Major Xanthophyll Carotenoids From Lettuce, and Assessment of Their Comparative Anticancer Potential. Food Chem. 2018 Nov 15;266:56-65.  [Content Brief]

    [3]. Akira Asai, et al. An Epoxide-Furanoid Rearrangement of Spinach Neoxanthin Occurs in the Gastrointestinal Tract of Mice and in Vitro: Formation and Cytostatic Activity of Neochrome Stereoisomers. J Nutr. 2004 Sep;134(9):2237-43.  [Content Brief]

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