Nifursol-13C6 is the 13C6 labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

371.17

C₆¹³C₆H₇N₅O₉

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

  [2]. Bowen TE, et al. Effect of cupric sulfate on the prophylactic efficacy of 2-acetylamino-5nitrothiazole, nifursol and ipronidazole against histomoniasis in turkeys. Poult Sci. 1971 Nov;50(6):1668-72.

  [3]. Jorge Barbosa, et al.Detection, accumulation, distribution, and depletion of furaltadone and nifursol residues in poultry muscle, liver, and gizzard. J Agric Food Chem. 2011 Nov 23;59(22):11927-34.