(S)-Higenamine (Synonyms: (S)-去甲乌药碱; (S)-Norcoclaurine)

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(S)-Higenamine  (Synonyms: (S)-去甲乌药碱; (S)-Norcoclaurine)

(S)-Higenamine ((S)-Norcoclaurine),Higenamine 的 S 型异构体,是苄基异喹啉生物碱生物合成的起始化合物,由去甲月桂碱合酶 (NCS) 将多巴胺和 4-羟基苯乙醛 (4-HPAA) 缩合生成。

(S)-Higenamine                                          (Synonyms: (S)-去甲乌药碱; (S)-Norcoclaurine)

(S)-Higenamine Chemical Structure

CAS No. : 22672-77-1

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(S)-Higenamine 的其他形式现货产品:

Higenamine hydrochloride (S)-Higenamine hydrobromide

(S)-Higenamine 相关产品

同靶点产品:

同靶点蛋白产品:

生物活性

(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

体外研究
(In Vitro)

The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-Higenamine 相关抗体:

分子量

271.31

Formula

C16H17NO3

CAS 号

22672-77-1

中文名称

(S)-去甲乌药碱

结构分类
  • Alkaloids
  • Isoquinoline Alkaloids
  • Phenols
  • Polyphenols
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (527 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.  [Content Brief]

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