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18-Oxocortisol 纯度: ≥98.0%
18-Oxocortisol 是由醛固酮合酶 (CYP11B2) 产生的皮质醇衍生物。18-Oxocortisol 是天然存在的盐皮质激素 (mineralocorticoid) 激动剂。18-Oxocortisol 是肾上腺静脉采样中的生物标志物。
18-Oxocortisol Chemical Structure
CAS No. : 2410-60-8
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥7200 | In-stock | |
| 5 mg | 询价 | ||
| 10 mg | 询价 |
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| 生物活性 |
18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling[1][2][3]. |
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| 体内研究 (In Vivo) |
Administration of 18-oxocortisol to rats induces a mineralocorticoid-type hypertension with hypokalemia, cardiac and renal enlargement and cardiovascular lesions. Administration of 18-oxocortisol to sheep also causes a rapid increase in blood pressure. However, the doses required for increasing blood pressure are high[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
376.44 |
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| Formula |
C21H28O6 |
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| CAS 号 |
2410-60-8 |
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| 性状 |
固体 |
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| 颜色 |
White to off-white |
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| 结构分类 |
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| 初始来源 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 纯度 & 产品资料 |
纯度: ≥98.0%
Data Sheet (531 KB) SDS (251 KB)
COA (174 KB) 产品使用指南 (1538 KB) |
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| 参考文献 |
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