标签归档：quinolone

1-Methyl-2-nonyl-4(1H)-quinolone

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1-Methyl-2-nonyl-4(1H)-quinolone 

1-Methyl-2-nonyl-4(1H)-quinolone 是一种喹诺酮类生物碱， 是一种有效的选择性的 MAO-B (单胺氧化酶)抑制剂。1-Methyl-2-nonyl-4(1H)-quinolone 对白三烯生物合成具有抑制活性，其 IC50 为 12.1 μM。

1-Methyl-2-nonyl-4(1H)-quinolone

1-Methyl-2-nonyl-4(1H)-quinolone Chemical Structure

CAS No. : 68353-24-2

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1-Methyl-2-nonyl-4(1H)-quinolone 相关产品

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生物活性

1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].

IC50 & Target

MAO-B

 

MAO-A

 

体外研究
(In Vitro)

1-Methyl-2-nonyl-4(1H)-quinolone shows more potent inhibitory effects against MAO-B compared to MAO-A[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

1-Methyl-2-nonyl-4(1H)-quinolone 相关抗体:
分子量

285.42

Formula

C19H27NO
CAS 号

68353-24-2
结构分类
  • Alkaloids
  • Quinoline Alkaloids
初始来源
  • 植物
  • 芸香科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (528 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401.  [Content Brief]

    [2]. Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8.  [Content Brief]

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