Taraxerol acetate (Synonyms: 醋酸蒲公英霜)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Taraxerol acetate  (Synonyms: 醋酸蒲公英霜)

Taraxerol acetate 是 COX-1COX-2 抑制剂, IC50 值分别为 116.3 μM 和 94.7μM。Taraxerol acetate 具有抗癌作用并诱导细胞凋亡(apoptosis)。

Taraxerol acetate                                          (Synonyms: 醋酸蒲公英霜)

Taraxerol acetate Chemical Structure

CAS No. : 2189-80-2

规格 价格 是否有货 数量
1 mg ¥850 1 周
5 mg ¥2100 1 周
10 mg ¥3400 1 周
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Taraxerol acetate 相关产品

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生物活性

Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].

IC50 & Target[1]

COX-1

116.3 μM (IC50)

COX-2

94.7 μM (IC50)

体外研究
(In Vitro)

Taraxerol acetate(10-150 µM; 24 or 48 hours) induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4 µM, at 24 and 48 h, respectively[2].
Taraxerol acetate(10, 50 and 150 µM; 24 hours) induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150 µM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1 cell cycle arrest with a corresponding decrease in the number of S-phase cells[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Taraxerol acetate 相关抗体:

分子量

468.75

Formula

C32H52O2

CAS 号

2189-80-2

中文名称

醋酸蒲公英霜

结构分类
  • Terpenoids
  • Triterpenes
初始来源
  • 植物
  • 豆科
  • Astragalus oleifolius DC.
  • 植物
  • 菊科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (527 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Ubaid Ur Rehman1 A, et al. Molecular docking of taraxerol acetate as a new COX inhibitor. Journal of the Bangladesh Pharmacological Society

    [2]. Hong JF, et al. Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration.Mol Med Rep. 2016 Jun;13(6):4541-8.  [Content Brief]

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