(-)-Taxifolin (Synonyms: (-)-二氢槲皮素; (-)-Dihydroquercetin)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
(-)-Taxifolin  (Synonyms: (-)-二氢槲皮素; (-)-Dihydroquercetin)

(-)-Taxifolin 是 Taxifolin 的低活性异构体。Taxifolin 具有重要的抗酪氨酸酶活性。Taxifolin 有效抑制胶原酶 (collagenase),IC50 为 193.3 μM。Taxifolin 是一种重要的天然化合物,具有抗纤维化作用。Taxifolin 是一种自由基清除剂具有抗氧化能力。

(-)-Taxifolin                                          (Synonyms: (-)-二氢槲皮素; (-)-Dihydroquercetin)

(-)-Taxifolin Chemical Structure

CAS No. : 111003-33-9

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生物活性

(-)-Taxifolin is the less active enantiomer of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].

分子量

304.25

Formula

C15H12O7

CAS 号

111003-33-9

中文名称

(-)-花旗松素;(-)-紫杉叶素;(-)-二氢槲皮素;(-)-黄杉素

结构分类
  • Flavonoids
  • Flavanonols
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21(11):1586.  [Content Brief]

    [2]. Lei Ren, et al. Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy. Front Pharmacol. 202  [Content Brief]

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