标签归档：terazosin

Terazosin (Synonyms: 特拉唑嗪)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Terazosin  (Synonyms: 特拉唑嗪)

Terazosin 是一种喹唑啉衍生物，也是一种竞争性和口服活性的 α1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂。Terazosin 通过舒张血管和打开膀胱来起作用。Terazosin 可用于良性前列腺增生 (BPH) 和高血压的研究。

Terazosin (Synonyms: 特拉唑嗪)

Terazosin Chemical Structure

CAS No. : 63590-64-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

Terazosin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Terazosin is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin works by relaxing blood vessels and the opening of the bladder. Terazosin has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3].

IC50 & Target

α1-adrenoceptor[1]
体外研究
(In Vitro)

Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Terazosin 相关抗体:
体内研究
(In Vivo)

Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

387.43

Formula

C19H25N5O4
CAS 号

63590-64-7
中文名称

特拉唑嗪
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (533 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Michel MC, et al. Drugs for treatment of benign prostatic hyperplasia: affinity comparison at cloned alpha 1-adrenoceptor subtypes and in human prostate. J Auton Pharmacol. 1996 Feb;16(1):21-8.  [Content Brief]

    [2]. Vincent J, et al. Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans. J Clin Invest. 1992 Nov;90(5):1763-8.  [Content Brief]

    [3]. Ju M, et al. Efficacy of combination terazosin and nifedipine therapy in postoperative treatment of distal ureteral stones after transurethral ureteroscopic lithotripsy. J Int Med Res. 2020 Apr;48(4):300060520904851.  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务