Tigloidin (Synonyms: Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin)

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Tigloidin  (Synonyms: Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin) 纯度: 99.91%

Tigloidin 是 atropine 的类似物,具有抗胆碱能的活性。

Tigloidin                                          (Synonyms: Tigloyl pseudotropine;  Tiglylpseudotropine;  Tiglyssin)

Tigloidin Chemical Structure

CAS No. : 495-83-0

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Tigloidin 相关产品

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生物活性

Tigloidin is an analogue of atropine, with anticholinergic activity.

体内研究
(In Vivo)

Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

223.31

Formula

C13H21NO2

CAS 号

495-83-0

性状

液体

颜色

Light yellow to yellow

结构分类
  • Alkaloids
初始来源
  • 植物
  • 茄科
  • 毛曼陀罗
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 99.91%

Data Sheet (530 KB) SDS (252 KB)

COA (192 KB) HNMR (200 KB) LCMS (103 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Sanghvi I, et al. Pharmacology of a potential anti-Parkinson agent: tigloidine. Eur J Pharmacol. 1968 Oct;4(3):246-53.  [Content Brief]

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