Toralactone (Synonyms: 决明内酯)

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Toralactone  (Synonyms: 决明内酯) 纯度: 98.75%

Toralactone 可从Cassia obtusifolia 中分离得到,通过 Nrf2 依赖的抗氧化机制介导肝保护。

Toralactone                                          (Synonyms: 决明内酯)

Toralactone Chemical Structure

CAS No. : 41743-74-2

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Toralactone 相关产品

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生物活性

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].

体外研究
(In Vitro)

Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Toralactone 相关抗体:

分子量

272.25

Formula

C15H12O5

CAS 号

41743-74-2

性状

固体

颜色

Off-white to yellow

中文名称

决明内酯

结构分类
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 苏木科
  • 钝叶决明
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 2.5 mg/mL (9.18 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.6731 mL 18.3655 mL 36.7309 mL
5 mM 0.7346 mL 3.6731 mL 7.3462 mL
10 mM

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* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

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浓度

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体积

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分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

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动物的平均体重

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每只动物的给药体积

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动物数量

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计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 98.75%

Data Sheet (597 KB) SDS (251 KB)

COA (195 KB) HNMR (256 KB) RP-HPLC (246 KB) MS (68 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. YongtaekSeo, et al. Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Research International. Volume 97, July 2017, Pages 340-346.

    [2]. Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.

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