Cytidine 5′-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA^[1][2].

CDP-ribitol 可用于CDP-l-核糖醇焦磷酸化酶A (CRPPA) 肌营养不良症的诊断和研究^[3]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

469.12

C₉H₁₂N₃Na₃O₁₁P₂

34393-59-4

固体

Off-white to light yellow

胞苷-5′-二磷酸三钠盐；胞苷5′-二磷酸三钠盐水合物；胞苷-5-二磷酸三钠盐

• Ketones, Aldehydes, Acids

• 内源性代谢物
• 人肠道微生物代谢物

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

H₂O 中的溶解度 : 250 mg/mL (532.91 mM; 超声助溶)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

• 方案 一

  请依序添加每种溶剂： PBS

  Solubility: 100 mg/mL (213.17 mM); 澄清溶液; 超声助溶

• [1]. Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018.  [Content Brief]

  [2]. Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417(4):431-47.  [Content Brief]

  [3]. Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65(10):1295-1306.  [Content Brief]